Nickel-catalyzed intermolecular oxidative Heck arylation driven by transfer hydrogenation

Abstract

Conventional palladium-catalyzed Heck reactions rely on the addition of oxidants and may suffer from low selectivity. Here, the authors report a nickel-catalyzed oxidative Heck arylation driven by transfer hydrogenation of an acceptor olefin leading to high E/Z selectivity and regioselectivity.