Zhongguo linchuang yanjiu (Feb 2023)
Effects of preoperative pre-rehabilitation on postoperative gastrointestinal function, nutritional status in patients with gastric cancer
Abstract
Objective To investigate the effects of preoperative pre-rehabilitation on postoperative gastrointestinal function, nutritional indicators, quality of life and adverse reactions in patients with gastric cancer. Methods A total of 66 patients who underwent radical gastrectomy for gastric cancer in the 901st Hospital of Joint Logistics Support Force of the CPLA from November 2019 to March 2022 were selected as the research subjects. The patients were divided into control group (n=35) and study group (n=31) by random number table method. The control group received routine preoperative preparation, and the study group received preoperative pre-rehabilitation. Postoperative gastrointestinal function recovery (first postoperative exhaust time, defecation time and the time to first oral feeding), serum nutritional indicators ［total protein (TP), albumin (Alb), prealbumin (PA) and hemoglobin (Hb)］, postoperative gastrointestinal adverse reactions during enteral nutrition, and the generic quality of life inventory-74 (GQOL-74) scores were compared between two groups. Results The time to first oral feeding, defecation recovery time and exhaust time in the study group after operation were significantly shorter than those in the control group (P<0.05). The levels of serum TP, Alb, PA, and Hb were higher in the study group than those in the control group on day 1, day 3 and day 7 after operation (P<0.05). The total incidence of gastrointestinal adverse reactions in the study group during postoperative enteral nutrition was significantly lower than that in the control group (6.45% vs25.71%, P<0.05). The scores of GQOL-74 of the two groups on day 7 after operation were higher than those on day 2 after operation, and the study group had higher scores than the control group (P<0.05).Conclusion Preoperative pre-rehabilitation can significantly improve postoperative gastrointestinal function and nutritional status, reduce the incidence of gastrointestinal adverse reactions, and promote the improvement of quality of life in patients undergoing radical gastrectomy for gastric cancer.
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