Italian Journal of Pediatrics (Apr 2021)
Inter-society consensus for the use of inhaled corticosteroids in infants, children and adolescents with airway diseases
- Marzia Duse,
- Francesca Santamaria,
- Maria Carmen Verga,
- Marcello Bergamini,
- Giovanni Simeone,
- Lucia Leonardi,
- Giovanna Tezza,
- Annamaria Bianchi,
- Annalisa Capuano,
- Fabio Cardinale,
- Giovanni Cerimoniale,
- Massimo Landi,
- Monica Malventano,
- Mariangela Tosca,
- Attilio Varricchio,
- Anna Maria Zicari,
- Carlo Alfaro,
- Salvatore Barberi,
- Paolo Becherucci,
- Roberto Bernardini,
- Paolo Biasci,
- Carlo Caffarelli,
- Valeria Caldarelli,
- Carlo Capristo,
- Serenella Castronuovo,
- Elena Chiappini,
- Renato Cutrera,
- Giovanna De Castro,
- Luca De Franciscis,
- Fabio Decimo,
- Iride Dello Iacono,
- Lucia Diaferio,
- Maria Elisa Di Cicco,
- Caterina Di Mauro,
- Cristina Di Mauro,
- Dora Di Mauro,
- Francesco Di Mauro,
- Gabriella Di Mauro,
- Mattia Doria,
- Raffaele Falsaperla,
- Valentina Ferraro,
- Vassilios Fanos,
- Elena Galli,
- Daniele Giovanni Ghiglioni,
- Luciana Indinnimeo,
- Ahmad Kantar,
- Adima Lamborghini,
- Amelia Licari,
- Riccardo Lubrano,
- Stefano Luciani,
- Francesco Macrì,
- Gianluigi Marseglia,
- Alberto Giuseppe Martelli,
- Luigi Masini,
- Fabio Midulla,
- Domenico Minasi,
- Vito Leonardo Miniello,
- Michele Miraglia del Giudice,
- Sergio Renzo Morandini,
- Germana Nardini,
- Agostino Nocerino,
- Elio Novembre,
- Giovanni Battista Pajno,
- Francesco Paravati,
- Giorgio Piacentini,
- Cristina Piersantelli,
- Gabriella Pozzobon,
- Giampaolo Ricci,
- Valter Spanevello,
- Renato Turra,
- Stefania Zanconato,
- Melissa Borrelli,
- Alberto Villani,
- Giovanni Corsello,
- Giuseppe Di Mauro,
- Diego Peroni
Affiliations
- Marzia Duse
- Department of Pediatrics, Policlinico Umberto I, Sapienza University of Rome
- Francesca Santamaria
- Department of Translational Medical Sciences, Federico II University
- Maria Carmen Verga
- Family Pediatrician Local Health Unit Salerno
- Marcello Bergamini
- Family Pediatrician, Local Health Unit
- Giovanni Simeone
- Family Pediatrician, Local Health Unit
- Lucia Leonardi
- Maternal, Infantile and Urological Sciences Department, Sapienza University
- Giovanna Tezza
- Pediatric Department, Franz Tappeiner Hospital
- Annamaria Bianchi
- Pediatric Unit, Department of Women’s and Children’s Health, San Camillo Forlanini Hospital
- Annalisa Capuano
- Department of Experimental Medicine, University “Luigi Vanvitelli”, Regional Centre of Pharmacovigilance Campania
- Fabio Cardinale
- Pediatric and Emergency Unit Giovanni XXIII Pediatric Hospital University of Bari
- Giovanni Cerimoniale
- Family Pediatrician Local Health Unit Latina
- Massimo Landi
- Family Pediatrician Local Health Unit, Turin and IRIB-CNR
- Monica Malventano
- Family Pediatrician, Local Health Unit
- Mariangela Tosca
- Family Pediatrician Local Health Unit
- Attilio Varricchio
- Allergy Centre, Department of Pediatric Sciences IRCCS Gaslini Institute
- Anna Maria Zicari
- Departmental Operative Unit of Diagnostic and Surgical Videoendoscopy of the Upper Airways
- Carlo Alfaro
- Maternal, infantile and urological sciences Department, Pediatric Allergic Unit, Sapienza University
- Salvatore Barberi
- Paediatrics Unit, Reunited Hospitals Castellammare of Stabia
- Paolo Becherucci
- Paediatric Unit, ASST-Rhodense
- Roberto Bernardini
- Family Pediatrician, Local Health Unit Tuscany center
- Paolo Biasci
- Pediatric Unit San Giuseppe Hospital
- Carlo Caffarelli
- Family Paediatrician, Local Health Unit, FIMP National President
- Valeria Caldarelli
- Medicine and Surgery Department, University of Parma
- Carlo Capristo
- Pediatric Unit, Department of Mother and Child, AUSL-IRCCS
- Serenella Castronuovo
- Department of Woman, Child and of General and Specialized Surgery, University “Luigi Vanvitelli”
- Elena Chiappini
- Family Paediatrician Local Health Unit Nettuno-Anzio
- Renato Cutrera
- Pediatric Pulmonology Unit, Academic Department of Paediatrics, Bambino Gesù Children’s Hospital, IRCCS
- Giovanna De Castro
- Departmental Operative Unit of Diagnostic and Surgical Videoendoscopy of the Upper Airways
- Luca De Franciscis
- Endocrinologist Specialist
- Fabio Decimo
- Pediatric Unit, Department of Mother and Child, AUSL-IRCCS
- Iride Dello Iacono
- Independent Paediatrician Researcher
- Lucia Diaferio
- Department of Paediatrics, Aldo Moro University of Bari
- Maria Elisa Di Cicco
- Paediatrics Unit, University Hospital of Pisa, Department of Clinical and Experimental Medicine, University of Pisa
- Caterina Di Mauro
- General Paediatrics and Paediatric Acute and Emergency Unit, University Hospital San Marco, University of Catania
- Cristina Di Mauro
- Department of Experimental Medicine, University “Luigi Vanvitelli”, Regional Centre of Pharmacovigilance Campania
- Dora Di Mauro
- Family Paediatrician Local Health Unit, Ausl
- Francesco Di Mauro
- Family Paediatrician, Local Health Unit
- Gabriella Di Mauro
- Department of Experimental Medicine, University “Luigi Vanvitelli”, Regional Centre of Pharmacovigilance Campania
- Mattia Doria
- Primary Care Paediatrician, Local Health Unit, National Secretary for the Scientific and Ethical Activities of FIMP
- Raffaele Falsaperla
- Neonatal Intensive Care Unit and Neonatal Accompaniment Unit, University Hospital San Marco, University of Catania
- Valentina Ferraro
- Unit of Paediatric Allergy and Respiratory Medicine Women’s and Children’s Health Department, University Hospital Padua
- Vassilios Fanos
- Neonatal Intensive Care Unit, Neonatal Pathology and Neonatal Section, AOU and University of Cagliari
- Elena Galli
- Pediatric Allergy Unit, Department of Paediatric Medicine, S. Pietro Hospital Fatebenefratelli
- Daniele Giovanni Ghiglioni
- Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico di Milano, UOSD Paediatric Highly Intensive Care Unit
- Luciana Indinnimeo
- Department of Pediatrics, Policlinico Umberto I, Sapienza University of Rome
- Ahmad Kantar
- Pediatric Asthma and Cough Center Istituti Ospedalieri Bergamaschi, Gruppo Ospedaliero San Donato
- Adima Lamborghini
- Family Pediatrician Local Health Unit Teramo
- Amelia Licari
- Paediatric and Neonatology Unit Santa Maria Goretti Hospital, Department of Pediatrics, University of Pavia
- Riccardo Lubrano
- Paediatric and Neonatology Unit Santa Maria Goretti Hospital, Department of Pediatrics, Sapienza University
- Stefano Luciani
- Pediatric and Neonatal Intensive Care Unit Fatebenefratelli Isola Tiberina
- Francesco Macrì
- Allergist Pediatrician National Secretary of Italian Federation for Medical Scientific Societies (FISM)
- Gianluigi Marseglia
- Paediatric and Neonatology Unit Santa Maria Goretti Hospital, Department of Pediatrics, University of Pavia
- Alberto Giuseppe Martelli
- Department of Pediatrics G. Salvini Hospital Garbagnate Milanese
- Luigi Masini
- Pediatric Pulmonology and Subintensive Respiratory Therapy Unit Department of Pediatrics Santobono-Pausilipon Children’s Hospital
- Fabio Midulla
- Maternal, Infantile and Urological Sciences Department, Sapienza University
- Domenico Minasi
- Pediatric Unit Great Metropolitan Hospital Reggio Calabria
- Vito Leonardo Miniello
- Department of Biomedical Science and Human Oncology, University of Bari, Children’s Hospital “Giovanni XXIII”
- Michele Miraglia del Giudice
- Pediatric Unit, Department of Mother and Child, AUSL-IRCCS
- Sergio Renzo Morandini
- Family Pediatrician Local Health Unit Latina
- Germana Nardini
- Family Pediatrician, Local Health Unit
- Agostino Nocerino
- Department of Translational Medical Sciences, Pediatric Pulmonology, Federico II University
- Elio Novembre
- Division of Pediatrics, University Hospital of Udine
- Giovanni Battista Pajno
- Department Health Science, University of Florence
- Francesco Paravati
- Department of Human Pathology in Adult and Development Age, Pediatric Unit, University of Messina
- Giorgio Piacentini
- Pediatric Unit, S. Giovanni di Dio Hospital
- Cristina Piersantelli
- Paediatric Section Department of Surgery, Dentistry, Paediatrics and Gynaecology University of Verona
- Gabriella Pozzobon
- Family Pediatrician, Paediatric Allergy, Local Health Unit TO1
- Giampaolo Ricci
- Department of Pediatrics, IRCC San Raffaele
- Valter Spanevello
- Alma Mater Studiorum, Univesity of Bologna
- Renato Turra
- Family Pediatrician Local Health Unit
- Stefania Zanconato
- Family Pediatrician Local Health Unit Caselle Torinese
- Melissa Borrelli
- Department of Translational Medical Sciences, Federico II University
- Alberto Villani
- Unit of Pediatric Allergy and Respiratory Medicine Women’s and Children’s Health Department University Hospital
- Giovanni Corsello
- Family Pediatrician, Local Health Unit Salerno
- Giuseppe Di Mauro
- Family Paediatrician, Local Health Unit
- Diego Peroni
- Department of Clinical and Experimental Medicine, Section of Pediatrics, University of Pisa
- DOI
- https://doi.org/10.1186/s13052-021-01013-8
- Journal volume & issue
-
Vol. 47,
no. 1
pp. 1 – 24
Abstract
Abstract Background In 2019, a multidisciplinary panel of experts from eight Italian scientific paediatric societies developed a consensus document for the use of inhaled corticosteroids in the management and prevention of the most common paediatric airways disorders. The aim is to provide healthcare providers with a multidisciplinary document including indications useful in the clinical practice. The consensus document was intended to be addressed to paediatricians who work in the Paediatric Divisions, the Primary Care Services and the Emergency Departments, as well as to Residents or PhD students, paediatric nurses and specialists or consultants in paediatric pulmonology, allergy, infectious diseases, and ear, nose, and throat medicine. Methods Clinical questions identifying Population, Intervention(s), Comparison and Outcome(s) were addressed by methodologists and a general agreement on the topics and the strength of the recommendations (according to the GRADE system) was obtained following the Delphi method. The literature selection included secondary sources such as evidence-based guidelines and systematic reviews and was integrated with primary studies subsequently published. Results The expert panel provided a number of recommendations on the use of inhaled corticosteroids in preschool wheezing, bronchial asthma, allergic and non-allergic rhinitis, acute and chronic rhinosinusitis, adenoid hypertrophy, laryngitis and laryngospasm. Conclusions We provided a multidisciplinary update on the current recommendations for the management and prevention of the most common paediatric airways disorders requiring inhaled corticosteroids, in order to share useful indications, identify gaps in knowledge and drive future research.
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