Albuterol–budesonide fixed-dose combination rescue inhaler for asthma: a plain language summary of the MANDALA study

Alberto Papi; Bradley E. Chipps; Richard Beasley; Reynold A. Panettieri; Elliot Israel; Mark Cooper; Lynn Dunsire; Allison Jeynes-Ellis; Robert Rees; Frank C. Albers; Christy Cappelletti

doi:10.1177/17534666241232264

Therapeutic Advances in Respiratory Disease (May 2024)

Albuterol–budesonide fixed-dose combination rescue inhaler for asthma: a plain language summary of the MANDALA study

Alberto Papi,
Bradley E. Chipps,
Richard Beasley,
Reynold A. Panettieri,
Elliot Israel,
Mark Cooper,
Lynn Dunsire,
Allison Jeynes-Ellis,
Robert Rees,
Frank C. Albers,
Christy Cappelletti

Affiliations

Alberto Papi: Department of Respiratory Medicine, University of Ferrara Medical School, Ferrara, Italy
Bradley E. Chipps: The Capital Allergy and Respiratory Disease Center, Sacramento, CA, USA
Richard Beasley: The Medical Research Institute of New Zealand; Capital and Coast District Health Board, and Victoria University of Wellington, Wellington, New Zealand
Reynold A. Panettieri: Rutgers Institute for Translational Medicine and Science; Child Health Institute of New Jersey, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA
Elliot Israel: Brigham and Women’s Hospital, Harvard Medical School, Boston, USA
Mark Cooper: BioPharmaceuticals Research and Development, AstraZeneca, Cambridge, UK
Lynn Dunsire: BioPharmaceuticals Research and Development, AstraZeneca, Cambridge, UK
Allison Jeynes-Ellis: Avillion, London, UK
Robert Rees: Avillion, London, UK
Frank C. Albers: Avillion, Northbrook, IL, USA
Christy Cappelletti: BioPharmaceuticals Research and Development, AstraZeneca, Durham, NC, USA

DOI: https://doi.org/10.1177/17534666241232264
Journal volume & issue: Vol. 18

Abstract

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What is this summary about? This summary describes the results of a clinical study called MANDALA that was published in the New England Journal of Medicine in 2022. In the MANDALA study, researchers looked at a new asthma rescue inhaler that contains both albuterol and budesonide in a single inhaler (known as albuterol–budesonide , AIRSUPRA™). This summary describes the results for people aged 18 yearsand older who took part in the study.

Published in Therapeutic Advances in Respiratory Disease

ISSN: 1753-4658 (Print); 1753-4666 (Online)
Publisher: SAGE Publishing
Country of publisher: United States
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system
Website: https://journals.sagepub.com/home/tar

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