Rhodium hydride enabled enantioselective intermolecular C–H silylation to access acyclic stereogenic Si–H

Abstract

Construction of chiral organosilicon compounds could have implications in photophysical, biological, and chemical fields, as silicon is isoelectronic with carbon, and can mimic carbon atoms while providing slightly different properties. Here the authors present an intermolecular, enantioselective C–H silylation of heterocycles via rhodium catalysis.