Excessive bacterial growth syndrome in smal intestine up-to-date diagnostics methods and approaches to therapeutic correction

Abstract

The article is devoted to one of the current issues of the internal medicine – to issues of diagnostics and therapeutic correction of the excessive bacterial growth syndrome (EBGS) in the small intestine. Consistent patterns of microflora dissemination in various departments of the gastrointestinal tract are provided, the “excessive bacterial growth syndrome” in the small intestine is defined. The most significant factors leading to small intestine microbiocoenosis disturbance are set forth. Possibilities of a number of diagnostic methods and their place for EBGS verification are determined. Major principles are therapeutic and preventive measures (treatment of pathology that led to its development; diet correction; decontamination of opportunistic flora, restoration of eubiosis; supporting therapy of the major disease and prevention of microbe contamination of the small intestine (in the period of remission)) are described. Taking into account current requirements presented to “ideal antibacterial drugs”, special place is given to rifaximin-α (Alfa Normix®) due to its high effectiveness and safety of use.

Keywords

• microflora
• “excessive bacterial growth syndrome” in small intestine (ebgs)
• diagnostics
• therapeutic and preventive measures
• antibacterial therapy
• rifaximin-α (alfa normix®)