Epidemiology of 369 diseases and injuries attributable to 84 risk factors: 1990–2019 with 2040 projection

Kexin Zhang; Chengxia Kan; Jian Chen; Junfeng Shi; Yanhui Ma; Xiaoli Wang; Xuan Li; Weiqin Cai; Ruiyan Pan; Jingwen Zhang; Zhentao Guo; Fang Han; Ningning Hou; Xiaodong Sun

iScience (Apr 2024)

Epidemiology of 369 diseases and injuries attributable to 84 risk factors: 1990–2019 with 2040 projection

Kexin Zhang,
Chengxia Kan,
Jian Chen,
Junfeng Shi,
Yanhui Ma,
Xiaoli Wang,
Xuan Li,
Weiqin Cai,
Ruiyan Pan,
Jingwen Zhang,
Zhentao Guo,
Fang Han,
Ningning Hou,
Xiaodong Sun

Affiliations

Kexin Zhang: Department of Endocrinology and Metabolism, Clinical Research Center, Affiliated Hospital of Shandong Second Medical University, Weifang, China
Chengxia Kan: Department of Endocrinology and Metabolism, Clinical Research Center, Affiliated Hospital of Shandong Second Medical University, Weifang, China
Jian Chen: School of Basic Medical Sciences, Guilin Medical University, Guilin, China
Junfeng Shi: Department of Endocrinology and Metabolism, Clinical Research Center, Affiliated Hospital of Shandong Second Medical University, Weifang, China
Yanhui Ma: Department of Pathology, Affiliated Hospital of Shandong Second Medical University, Weifang, China
Xiaoli Wang: School of Medical Imaging, Weifang Medical University, Weifang, China
Xuan Li: Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA
Weiqin Cai: School of Management, Weifang Medical University, Weifang, China
Ruiyan Pan: Department of Pharmacy, Weifang Medical University, Weifang, China
Jingwen Zhang: Department of Endocrinology and Metabolism, Clinical Research Center, Affiliated Hospital of Shandong Second Medical University, Weifang, China
Zhentao Guo: Department of Nephrology, Affiliated Hospital of Shandong Second Medical University, Weifang, China; Corresponding author
Fang Han: Department of Pathology, Affiliated Hospital of Shandong Second Medical University, Weifang, China; Corresponding author
Ningning Hou: Department of Endocrinology and Metabolism, Clinical Research Center, Affiliated Hospital of Shandong Second Medical University, Weifang, China; Corresponding author
Xiaodong Sun: Department of Endocrinology and Metabolism, Clinical Research Center, Affiliated Hospital of Shandong Second Medical University, Weifang, China; Corresponding author

Journal volume & issue: Vol. 27, no. 4
p. 109508

Abstract

Read online

Summary: The global burden of diseases and injuries poses complex and pressing challenges. This study analyzed 369 diseases and injuries attributed to 84 risk factors globally from 1990 to 2019, projecting trends to 2040. In 2019, global risks caused 35 million deaths. Non-communicable diseases were responsible for 8.2 million deaths, primarily from air pollution (5.5 million). Cardiovascular disease from air pollution had a high age-standardized disability-adjusted life year rate (1,073.40). Communicable, maternal, neonatal, and nutritional diseases caused 1.4 million deaths, mainly due to unsafe water and sanitation. Occupational risks resulted in 184,269 transport-related deaths. Behavioral risks caused 21.6 million deaths, with dietary factors causing 6.9 million cardiovascular deaths. Diabetes linked to sugar-sweetened beverages showed significant growth (1990–2019). Metabolic risks led to 18.6 million deaths. Projections to 2040 indicated persistent challenges, emphasizing the urgent need for targeted interventions and policies to alleviate the global burden of diseases and injuries.

Published in iScience

ISSN: 2589-0042 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Science
Website: http://www.cell.com/iscience/home

About the journal

Abstract

Keywords