Hereditary systemic transthyretin amyloidosis: a clinical case and an opinion on the problem

Abstract

This article presents a clinical case of a patient with hereditary systemic hereditary transthyretin amyloidosis. Difficulties of diagnostics and differential diagnostics of this disease are shown in a patient with arterial hypertension, a clinic of angina, coronary artery disease, cardiac rhythm and conduction disturbances, cardiomegaly, heart failure and renal dysfunction. It required a comprehensive approach using the methods of routine clinical and laboratory examination, as well as nuclear cardiology, morphological studies and molecular DNA diagnostics.

Keywords

• transthyretin amyloidosis
• hereditary amyloidosis
• systemic amyloidosis
• heart failure