Transforming insect population control with precision guided sterile males with demonstration in flies

Nikolay P. Kandul; Junru Liu; Hector M. Sanchez C.; Sean L. Wu; John M. Marshall; Omar S. Akbari

doi:10.1038/s41467-018-07964-7

Nature Communications (Jan 2019)

Transforming insect population control with precision guided sterile males with demonstration in flies

Nikolay P. Kandul,
Junru Liu,
Hector M. Sanchez C.,
Sean L. Wu,
John M. Marshall,
Omar S. Akbari

Affiliations

Nikolay P. Kandul: Division of Biological Sciences, Section of Cell and Developmental Biology, University of California, San Diego
Junru Liu: Division of Biological Sciences, Section of Cell and Developmental Biology, University of California, San Diego
Hector M. Sanchez C.: Division of Biostatistics and Epidemiology, School of Public Health, University of California
Sean L. Wu: Division of Biostatistics and Epidemiology, School of Public Health, University of California
John M. Marshall: Division of Biostatistics and Epidemiology, School of Public Health, University of California
Omar S. Akbari: Division of Biological Sciences, Section of Cell and Developmental Biology, University of California, San Diego

DOI: https://doi.org/10.1038/s41467-018-07964-7
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 12

Abstract

Read online

Sterile Insect Technique (SIT) is used to suppress wild populations. Here the authors integrate CRISPR-based technology and SIT to develop a precision guided SIT (pgSIT), and demonstrate its proof-of-principle by generating 100% sterile males.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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