Improvement of non‐alcoholic fatty liver disease after laparoscopic sleeve gastrectomy in Japanese obese patients

Abstract

Abstract Purpose The purpose of this study was to evaluate changes in non‐alcoholic fatty liver disease (NAFLD) after laparoscopic sleeve gastrectomy (LSG) using computed tomography (CT) images. Methods We analyzed data from 57 patients who underwent LSG and had CTs performed before and after surgery. The patients included 34 women and 23 men (with an average age of 43 years); their mean preoperative weight and body mass index were 120 kg and 46 kg/m2, respectively. Obesity‐related health disorders included type 2 diabetes mellitus (T2DM) in 33 patients, hypertension in 33 and dyslipidemia in 32. We diagnosed NAFLD in cases with liver to spleen ratios (L/S ratio) 0.9. We diagnosed 33 out of 57 patients (58%) as having NAFLD before the operation. After the operation, the L/S ratios and liver volumes were not statistically different between the patients with previous NAFLD and those without it. Conclusion Laparoscopic sleeve gastrectomy is an effective treatment for obesity‐related health disorders including NAFLD in Japanese obese patients.

Keywords

• bariatric surgery
• laparoscopic sleeve gastrectomy
• liver to spleen ratio
• liver volume
• non‐alcoholic fatty liver disease