Circadian Variation Of Stroke Onset

Abstract

Diurnal variations in various physiological and biochemical functions and certain pathological events like myocardial infarction and stroke have been documented. We studied prospectively one hundred and seven patients of acute onset stroke confirmed by computed tomography for the exact time of onset, risk factors and type of stroke. Patients who were unclear of time of onset and with a diagnosis of cerebral venous thrombosis or sub-arachnoid hemorrhage were excluded. Infarction was detected in 71 patients and hemorrhage in 33 patients. Men out numbered women (1:6:1). Hypertension was more frequent in hemorrhage in the morning time (5 AM-12 noon) and more infarction between 12-6 pm. However there was no relation between the time of onset of stroke and various risk-factors of stroke.