Nature Communications (May 2019)

The Pseudomonas aeruginosa lectin LecB binds to the exopolysaccharide Psl and stabilizes the biofilm matrix

  • Daniel Passos da Silva,
  • Michael L. Matwichuk,
  • Delaney O. Townsend,
  • Courtney Reichhardt,
  • Doriano Lamba,
  • Daniel J. Wozniak,
  • Matthew R. Parsek

DOI
https://doi.org/10.1038/s41467-019-10201-4
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 11

Abstract

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Pseudomonas aeruginosa biofilms are composed of exopolysaccharides, exogenous DNA, and proteins. Here, da Silva et al show that protein LecB binds to matrix exopolysaccharide Psl, thus contributing to increased retention of bacterial cells and exopolysaccharide in growing biofilms.