Evolution of a Multiple Sex-Chromosome System by Three-Sequential Translocations among Potential Sex-Chromosomes in the Taiwanese Frog <i>Odorrana swinhoana</i>

Ikuo Miura; Foyez Shams; Si-Min Lin; Marcelo de Bello Cioffi; Thomas Liehr; Ahmed Al-Rikabi; Chiao Kuwana; Kornsorn Srikulnath; Yuya Higaki; Tariq Ezaz

doi:10.3390/cells10030661

Cells (Mar 2021)

Evolution of a Multiple Sex-Chromosome System by Three-Sequential Translocations among Potential Sex-Chromosomes in the Taiwanese Frog <i>Odorrana swinhoana</i>

Ikuo Miura,
Foyez Shams,
Si-Min Lin,
Marcelo de Bello Cioffi,
Thomas Liehr,
Ahmed Al-Rikabi,
Chiao Kuwana,
Kornsorn Srikulnath,
Yuya Higaki,
Tariq Ezaz

Affiliations

Ikuo Miura: Amphibian Research Center, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima 739-8526, Japan
Foyez Shams: Center for Conservation Ecology and Genomics, University of Canberra, Canberra, ACT 2601, Australia
Si-Min Lin: Amphibian Research Center, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima 739-8526, Japan
Marcelo de Bello Cioffi: Departamento de Genética e Evolução, Universidade Federal de São Carlos, São Carlos 13565-090, SP, Brazil
Thomas Liehr: Institute of Human Genetics, University Hospital Jena, Am Klinikum 1, 07747 Jena, Germany
Ahmed Al-Rikabi: Institute of Human Genetics, University Hospital Jena, Am Klinikum 1, 07747 Jena, Germany
Chiao Kuwana: Graduate School of Integrated Sciences for Life, Hiroshima University, 1-4-4 Kagamiyama, Higashi-Hiroshima 739-8528, Japan
Kornsorn Srikulnath: Amphibian Research Center, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima 739-8526, Japan
Yuya Higaki: Graduate School of Integrated Sciences for Life, Hiroshima University, 1-4-4 Kagamiyama, Higashi-Hiroshima 739-8528, Japan
Tariq Ezaz: Amphibian Research Center, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima 739-8526, Japan

DOI: https://doi.org/10.3390/cells10030661
Journal volume & issue: Vol. 10, no. 3
p. 661

Abstract

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Translocation between sex-chromosomes and autosomes generates multiple sex-chromosome systems. It happens unexpectedly, and therefore, the evolutionary meaning is not clear. The current study shows a multiple sex chromosome system comprising three different chromosome pairs in a Taiwanese brown frog (Odorrana swinhoana). The male-specific three translocations created a system of six sex-chromosomes, ♂X1Y1X2Y2X3Y3-♀X1X1X2X2X3X3. It is unique in that the translocations occurred among three out of the six members of potential sex-determining chromosomes, which are known to be involved in sex-chromosome turnover in frogs, and the two out of three include orthologs of the sex-determining genes in mammals, birds and fishes. This rare case suggests sex-specific, nonrandom translocations and thus provides a new viewpoint for the evolutionary meaning of the multiple sex chromosome system.

Published in Cells

ISSN: 2073-4409 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Biology (General): Cytology
Website: https://www.mdpi.com/journal/cells

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