Prevalence of Allergic Fungal Rhinosinusitis Among Patients with Nasal Polyps

Abstract

Objective: The objective of the study was to determine the frequency of allergic fungal rhinosinusitis among patients with nasal polyps. Methods: This study was performed at Department of ENT and Head Surgery, Jinnah Post Graduate Medical Center, Karachi during July 2018 to January 2019. Patients with nasal polyp fulfilling the inclusion criteria were enrolled. Sino-nasal contents were removed during operation and divided into two parts. Sample one was preserved in formalin solution and sent for histopathology to verify eosinophilic mucin and polyps. Another sample was preserved in 10% of potassium hydroxide solution to observe fungal hyphae by culture and fungal staining SPSS v-23.0 was used for the analysis. Results: Total of one hundred and fifty patients was included in the present study. There were sixtyone females (40.7%) and eighty-nine (59.3%) males. The mean age of patients was 30.5 ± 11.4 years. Out of 150 patients with nasal polyps, 33(22.0%) had allergic fungal rhino sinusitis (AFRS). In this study, it was found that, AFRS was associated with gender and smoking (p=0.036). Conclusion: AFRS is perceived generally among patients with nasal polyps. In this way, each patient with nasal polyp ought to be assessed for the existence of AFRS

Keywords

• Nasal Polyps
• Rhinitis
• Allergic IgE
• mucins