miR-9a modulates maintenance and ageing of Drosophila germline stem cells by limiting N-cadherin expression

Abstract

In the Drosophila testis, ageing leads to loss of germline stem cells. Here, the authors show that, during ageing in Drosophila, miR-9a is upregulated in male germline stem cells and regulates their proliferation by targeting N-cadherin.