Sensitivity of the skin test with tuberculous allergen in TB/HIV patients

Abstract

The sensitivity of skin test with tuberculous allergen in TB/HIV patients has need studied (n = 36) depending on the immune deficiency and the character of tuberculous inflammation. The comparison group included patients with HIV infection and no tuberculosis (n = 54). The test results in HIV patients but without tuberculosis and in the patients with the concurrent condition are directly connected to the degree of immune deficiency. In the patients with HIV infection and progressing tuberculosis the negative results of the test are due to secondary anergy. The patients with severe and expressed immune deficiency the negative results do not exclude the activeness of the infection, thus patients with CD4 level up to 350 + cl/mcl and negative results can be referred as a group of high risk of developing tuberculosis.

Keywords

• туберкулез
• вич-инфекция
• аллерген туберкулезный
• кожная проба с диаскинтестом
• активность туберкулезной инфекции
• иммунодефицит