1147-E UI-101, a TLR7/8 agonist encapsulated in cholesteryl pullulan nanoparticle targeting tumor-associated macrophages via binding to DC-SIGN, elicits potent anti-tumor immunity without severe side effect

• Yuka Igarashi,
• Ayaka Matsumoto,
• Tadashi Inoue,
• Yasunari Haseda,
• Nami Mizoguchi,
• Junki Tashiro,
• Takatoshi Soga,
• Naozumi Harada

Affiliations

Yuka Igarashi

United Immunity, Co., Ltd., Kobe, Hyogo, Japan

Ayaka Matsumoto

United Immunity, Co., Ltd., Kobe, Hyogo, Japan

Tadashi Inoue

United Immunity, Co., Ltd., Kobe, Hyogo, Japan

Yasunari Haseda

United Immunity, Co., Ltd., Kobe, Hyogo, Japan

Nami Mizoguchi

United Immunity, Co., Ltd., Kobe, Hyogo, Japan

Junki Tashiro

United Immunity, Co., Ltd., Kobe, Hyogo, Japan

Takatoshi Soga

United Immunity, Co., Ltd., Kobe, Hyogo, Japan

Naozumi Harada

United Immunity, Co., Ltd., Kobe, Hyogo, Japan