Nature Communications (May 2021)
Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo
- Yuming Zhang,
- Wenxuan Zhao,
- Yuncong Chen,
- Hao Yuan,
- Hongbao Fang,
- Shankun Yao,
- Changli Zhang,
- Hongxia Xu,
- Nan Li,
- Zhipeng Liu,
- Zijian Guo,
- Qingshun Zhao,
- Yong Liang,
- Weijiang He
Affiliations
- Yuming Zhang
- State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University
- Wenxuan Zhao
- State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University
- Yuncong Chen
- State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University
- Hao Yuan
- State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University
- Hongbao Fang
- State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University
- Shankun Yao
- State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University
- Changli Zhang
- School of Environmental Science, Nanjing Xiaozhuang University
- Hongxia Xu
- State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University
- Nan Li
- Model Animal Research Center, Nanjing University
- Zhipeng Liu
- College of Materials Science and Engineering, Nanjing Forestry University
- Zijian Guo
- State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University
- Qingshun Zhao
- Model Animal Research Center, Nanjing University
- Yong Liang
- State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University
- Weijiang He
- State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University
- DOI
- https://doi.org/10.1038/s41467-021-22855-0
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 10
Abstract
Most fluorescence probes to measure hypoxia are irreversible. Here, the authors develop a near infrared luminescent probe to measure hypoxia which is reversible and use the probe to monitor hypoxia-reoxygenation in several animal models.
