JAK2 V617F hematopoietic clones are present several years prior to MPN diagnosis and follow different expansion kinetics

• Thomas McKerrell,
• Naomi Park,
• Jianxiang Chi,
• Grace Collord,
• Thaidy Moreno,
• Hannes Ponstingl,
• Joao Dias,
• Petroula Gerasimou,
• Kiki Melanthiou,
• Chrystalla Prokopiou,
• Marios Antoniades,
• Ignacio Varela,
• Paul A. Costeas,
• George S. Vassiliou

Affiliations

Thomas McKerrell

The Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom;; Department of Haematology, University of Cambridge, Cambridge, United Kingdom;; Department of Haematology, Cambridge University Hospitals National Health Service Foundation Trust, Cambridge, United Kingdom;

Naomi Park

The Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom;

Jianxiang Chi

The Center for the Study of Haematological Malignancies, Nicosia, Cyprus;; The Karaiskakio Foundation, Nicosia, Cyprus;

Grace Collord

The Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom;

Thaidy Moreno

Instituto de Biomedicina y Biotecnología de Cantabria, Santander, Spain;

Hannes Ponstingl

The Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom;

Joao Dias

Cancer Molecular Diagnosis Laboratory, National Institute for Health Research Biomedical Research Centre, University of Cambridge, Cambridge, United Kingdom;

Petroula Gerasimou

The Center for the Study of Haematological Malignancies, Nicosia, Cyprus;; The Karaiskakio Foundation, Nicosia, Cyprus;

Kiki Melanthiou

Department of Haematology, Nicosia General Hospital, Nicosia, Cyprus

Chrystalla Prokopiou

Department of Haematology, Limassol General Hospital, Limassol, Cyprus

Marios Antoniades

Department of Haematology, Nicosia General Hospital, Nicosia, Cyprus

Ignacio Varela

Instituto de Biomedicina y Biotecnología de Cantabria, Santander, Spain;

Paul A. Costeas

The Center for the Study of Haematological Malignancies, Nicosia, Cyprus;; The Karaiskakio Foundation, Nicosia, Cyprus;; Paul A. Costeas, The Karaiskakio Foundation, Nicosia, Cyprus;.

George S. Vassiliou

The Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom;; Department of Haematology, University of Cambridge, Cambridge, United Kingdom;; Department of Haematology, Cambridge University Hospitals National Health Service Foundation Trust, Cambridge, United Kingdom;; The Center for the Study of Haematological Malignancies, Nicosia, Cyprus;; George S. Vassiliou, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom;