Efficacy of vacuum sealing drainage combined with ultrasonic debridement surgical system on gouty

Abstract

Objective To investigate the clinical effects and safety of vacuum sealing drainage (VSD) combined with ultrasonic debridement surgical system (UDSS) on the patients with gouty tophus ulceration. Methods Totally 96 patients suffering from gout and gouty tophus ulceration admitted in our department from September 2014 to December 2017 were recruited, and then randomly divided into 2 groups (n=48 for each group). The patients from the experiment group (51.3±7.6 years old, disease course of 6.8±1.1 years, BMI 25.7±1.2, wound area 1.62±0.23 cm2) were treated with UDSS combined VSD, and those from the control group (52.4±6.9 years old, disease course of 6.5±1.3 years, BMI 26.1±1.4, wound area 1.65±0.21 cm2) were treated with conventional surgical debridement. Wound healing, cure rate, effective rate, visual analogue scale (VAS) score before and after treatment, cost of hospitalization, and incidences of adverse reactions were observed and compared between the 2 groups. Results Compared with the control group, the experimental group obtained better wound healing (P 0.05). Two cases (4.2%) from the experimental group experienced acute pain in affected area during ultrasonic debridement, and 3 cases (6.3%) had delayed healing. Conclusion UDSS combined with VSD can accelerate wound healing, improve healing outcome, and have no effect on the costs of hospitalization or incidences of adverse reactions.

Keywords

• tophi
• ultrasonic debridement
• vacuum sealing drainage
• wound