Marked Sinus Bradycardia Associated With Remdesivir in COVID-19

James C. Gubitosa, DO; Parul Kakar, MD; Christine Gerula, MD; Hernando Nossa, MD; Diana Finkel, MD; Kristin Wong, MD; Megna Khatri, MD; Hasan Ali, DO

JACC: Case Reports (Nov 2020)

Marked Sinus Bradycardia Associated With Remdesivir in COVID-19

James C. Gubitosa, DO,
Parul Kakar, MD,
Christine Gerula, MD,
Hernando Nossa, MD,
Diana Finkel, MD,
Kristin Wong, MD,
Megna Khatri, MD,
Hasan Ali, DO

Affiliations

James C. Gubitosa, DO: Department of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey; Address for correspondence: Dr. James C. Gubitosa, Department of Medicine, Rutgers New Jersey Medical School, 185 S. Orange Avenue, Newark, New Jersey 07103.
Parul Kakar, MD: Department of Cardiology, Rutgers New Jersey Medical School, Newark, New Jersey
Christine Gerula, MD: Department of Cardiology, Rutgers New Jersey Medical School, Newark, New Jersey
Hernando Nossa, MD: Department of Infectious Disease, Rutgers New Jersey Medical School, Newark, New Jersey
Diana Finkel, MD: Department of Infectious Disease, Rutgers New Jersey Medical School, Newark, New Jersey
Kristin Wong, MD: Department of Medicine-Pediatrics, Rutgers New Jersey Medical School, Newark, New Jersey
Megna Khatri, MD: Department of Medicine-Pediatrics, Rutgers New Jersey Medical School, Newark, New Jersey
Hasan Ali, DO: Department of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey

Journal volume & issue: Vol. 2, no. 14
pp. 2260 – 2264

Abstract

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Remdesivir has seen extensive use during the coronavirus disease-2019 pandemic given its clinically proven efficacy against severe acute respiratory syndrome coronavirus type 2. There has been little cited regarding adverse effects. Here we present the case of a patient with marked sinus bradycardia that began acutely on initiation of remdesivir and resolved almost immediately on cessation of the drug. (Level of Difficulty: Beginner.)

Published in JACC: Case Reports

ISSN: 2666-0849 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system
Website: https://www.journals.elsevier.com/jacc-case-reports

About the journal

Abstract

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