P1421: BIMODAL TARGETING OF CYTOKINE RECEPTOR-LIKE FACTOR 2 (CRLF2) WITH JAK INHIBITION AND CHIMERIC ANTIGEN RECEPTOR T CELL IMMUNOTHERAPY IN DOWN SYNDROME ACUTE LYMPHOBLASTIC LEUKEMIA

• A. Bagashev,
• J. Loftus,
• L. Niswander,
• S. Ross,
• C. D. Falkenstein,
• J. Junco,
• K. R. Rabin,
• T. Fry,
• S. K. Tasian

Affiliations

A. Bagashev

1 Oncology, Children’s Hospital of Philadelphia, Philadelphia

J. Loftus

1 Oncology, Children’s Hospital of Philadelphia, Philadelphia

L. Niswander

1 Oncology, Children’s Hospital of Philadelphia, Philadelphia

S. Ross

2 Children’s Hospital Colorado, Denver

C. D. Falkenstein

3 Children’s Hospital of Philadelphia, Philadelphia

J. Junco

4 Texas Children’s Hospital, Houston, United States of America

K. R. Rabin

4 Texas Children’s Hospital, Houston, United States of America

T. Fry

2 Children’s Hospital Colorado, Denver

S. K. Tasian

3 Children’s Hospital of Philadelphia, Philadelphia