Boron Neutron Capture Therapy Eliminates Radioresistant Liver Cancer Cells by Targeting DNA Damage and Repair Responses [Corrigendum]

Abstract

Huang CY, Lai ZY, Hsu TJ, Chou FI, Liu HM, Chuang YJ. J Hepatocell Carcinoma. 2022;9:1385–1401. The authors have advised due to an error at the time of figure assembly, Figure 7A on page 1395 is incorrect. The western blots for the 10-hour timepoint in Figure 7A was duplicated from the western blots of the 24-hour timepoint in Figure 7B. The correct Figure 7 is shown below. Figure 7 Boron neutron capture therapy increased G2/M arrest by altering CHK2 and CDK1 (CDC2) checkpoint signaling. Western blot assay for the G2/M checkpoint regulation-related proteins pCHK2, CHK2, pCDK1 (CDC2) (Y15), pCDK1 (pCDC2) (T161), and CDK1 (CDC2) at 10 hours (A) and 24 hours (B) post-irradiation. *p<0.05, **p<0.01, ***p<0.001. The authors apologize for this error and advise it does not affect the results of the paper.

Keywords

• boron neutron capture therapy
• bnct
• hepatocellular carcinoma
• hcc
• radioresistance
• dna damage
• dna repair responses