Archives of Endocrinology and Metabolism (Jun 2024)

Effect of fasting glucose levels on carotid intima-media thickness in premenopausal versus postmenopausal women

  • Ren Xia,
  • Su Fan,
  • Hu Jian,
  • Cao Lei,
  • Mei Wendan,
  • Wang Chenxu,
  • Fang Yicheng,
  • Grace Tavengana,
  • Jiang Mingfei,
  • Wu Huan,
  • Wen Yufeng

DOI
https://doi.org/10.20945/2359-4292-2023-0110
Journal volume & issue
Vol. 68

Abstract

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ABSTRACT Objective: To investigate the relationship between fasting blood glucose (FBG) and carotid intima-media thickness (IMT) in premenopausal and postmenopausal women. Subjects and methods: The study enrolled 2,959 women seen at the Maanshan People's Hospital of Anhui Province from December 2013 to December 2018. Carotid IMT was measured using Doppler ultrasound. Linear regression and R smoothing curves were used to analyze the relationship between blood glucose level and carotid IMT in the premenopausal and postmenopausal groups. Results: Postmenopausal compared with premenopausal women had higher mean IMT (mIMT; 0.81 ± 0.23 mm versus 0.70 ± 0.14 mm, respectively, p 10 mmol/L in the postmenopausal group. Conclusion: Levels of FBG contributed more to increased IMT in postmenopausal than premenopausal women. The influence of FBG was greater on maxIMT than mIMT. Additionally, FBG was helpful in assessing focal thickening of the carotid intima.

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