Abstract 1122‐000184: Cerebral Arterial Variations in Patients with Ischemic Stroke Undergoing Mechanical Thrombectomy

Abstract

Introduction: This study aimed to determine what anatomical variants of the Circle of Willis (CoW) and the middle cerebral artery(MCA) are observed in patients with acute M1 occlusion and whether their prevalence differs from that described as “normal” in anatomy textbooks. Methods: We have performed a retrospective assessment of radiological examinations of patients with stroke due to middle cerebral artery M1 segment occlusion. All patients underwent mechanical thrombectomy from January 2015 until March 2021. The anatomy of the CoW was assessed on initial CT‐angiography and DSA. Branches of the MCA were observed on control DSA after recanalization. Results: A total of 100 patients were included in the analysis (58 females and 42 males, mean age: 71.6 +/‐ 13.9). Fully complete CoW was observed in 19% of patients. A total of 10% of patients had an incomplete anterior portion of CoW. In the incomplete anterior portion subgroup, the most common variation was the absence of anterior communicating artery (6% of total hemispheres), followed by the absence of one A1 (3% of total hemispheres). An incomplete posterior portion of CoW was identified in 79% of the patients. The absence of posterior communicating artery (PCoA) was observed in 59 patients. Sixteen patients had adult‐type PCoA, 3 patients had transitional‐type PCoA and 21 patients had fetal‐type posterior cerebral artery (PCA). In the subgroup of patients with fetal‐type posterior circle, 5 patients had no P1 segment of PCA. Anterior temporal branch of MCA was observed in 45% of the patients. Middle cerebral artery bifurcation was found in 80% of hemispheres, and trifurcation in 20%. In the bifurcation subgroup, 26% of MCAs had a dominating upper branch and 18% had a dominating lower branch. A duplicate MCA was observed in one hemisphere. Conclusions: In comparison to normal anatomy described in anatomy textbooks, the population of patients suffering from ischemic stroke due to M1 occlusion had a lower proportion of complete and closed CoW. A foetal type PCoA was observed to be prevalent (21%) in patients suffering from acute M1 occlusion. Detailed anatomical knowledge of anatomical variants of CoW in patients undergoing mechanical thrombectomy is essential for clinicians performing intravascular interventions and may aid procedure planning.

Keywords

• Cerebral Blood Flow
• Imaging
• Angiographic Ct
• Interventional Neuroradiology