Journal of Evidence-Based Healthcare (Mar 2023)

Prevalence of Diabetes Mellitus among individuals with chronic kidney disease: systematic review and meta-analysis

  • Luiza Delazari Borges,
  • Heloísa Helena Dias,
  • Emily de Souza Ferreira,
  • Paulyenny Machado Alves,
  • Beatriz Oliveira Silva,
  • Kíllya de Paiva Santos,
  • Glauce Dias da Costa,
  • Tiago Ricardo Moreira,
  • Daniel Souza Santos,
  • Rosângela Minardi Mitre Cotta

DOI
https://doi.org/10.17267/2675-021Xevidence.2023.e4060
Journal volume & issue
Vol. 5

Abstract

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BACKGROUND: Diabetes Mellitus (DM) is currently considered a global epidemic, with alarming estimates for the coming years on all continents, with Chronic Kidney Disease (CKD) as one of its main consequences when a timely diagnosis is not made. OBJECTIVE: The objective of this study is to estimate the prevalence of DM among individuals diagnosed with CKD by means of a systematic review and meta-analysis. METHODS: A systematic review was carried out in the main free-access databases such as Pubmed (Medlaine), Lilacs, Scopus and Scielo. Two researchers selected the articles, extracted the data and evaluated the quality. The collected data were evaluated using a random effects model. RESULTS: Of 994 articles, 17 studies were included that looked at three continents. The group prevalence of DM among individuals with CKD (95% CI) was 29% (23-35%), with heterogeneity I2 = 99,86% and p = 0.00, which was not explained by meta-regression and subgroups. CONCLUSIONS: The present study confirmed the high prevalence of DM among individuals with CKD, especially among those with end-stage renal disease, demonstrating the need for early diagnosis and timely treatment of DM and new studies in this area, considering the social and economic impact of these diseases worldwide.

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