Efficacy and cost-effectiveness of Stem Cell injections for symptomatic relief and strUctural improvement in people with Tibiofemoral knee OsteoaRthritis: protocol for a randomised placebo-controlled trial (the SCUlpTOR trial)

• Leticia A Deveza,
• Win Min Oo,
• Stefan Lohmander,
• Xia Wang,
• Changhai Ding,
• Felix Eckstein,
• Wolfgang Wirth,
• Anthony Harris,
• Xiaoqian Liu,
• Sarah Robbins,
• Sonika Virk,
• Benny Antony,
• David Humphries,
• Christopher Little,
• James Linklater,
• Gillian Heller,
• Karen Schuck,
• Kirsty Carmichael,
• R O'Connell,
• Thomas Buttel

Affiliations

Leticia A Deveza

Department of Rheumatology, Royal North Shore Hospital, Northern Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia

Win Min Oo

Department of Rheumatology, Royal North Shore Hospital, Northern Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia

Stefan Lohmander

Department of Clinical Sciences Lund, Orthopaedics, Lund University, Lund, Sweden

Xia Wang

Department of Rheumatology, Royal North Shore Hospital, Northern Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia

Changhai Ding

Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia

Felix Eckstein

Institute of Anatomy and Cell Biology and Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Paracelsus Medical University Salzburg, Salzburg, Austria

Wolfgang Wirth

Institute of Anatomy and Cell Biology and Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Paracelsus Medical University Salzburg, Salzburg, Austria

Anthony Harris

Centre for Health Economics, Monash University, Clayton, Victoria, Australia

Xiaoqian Liu

Department of Rheumatology, Royal North Shore Hospital, Northern Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia

Sarah Robbins

Department of Rheumatology, Royal North Shore Hospital, Northern Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia

Sonika Virk

Department of Rheumatology, Royal North Shore Hospital, Northern Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia

Benny Antony

Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia

David Humphries

School of Medicine, College of Health and Medicine, University of Tasmania Faculty of Health, Hobart, Tasmania, Australia

Christopher Little

Raymond Purves Bone and Joint Research Labs, Kolling Institute of Medical Research, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia

James Linklater

Castlereagh Imaging, St Leonards, Sydney, New South Wales, Australia

Gillian Heller

NHMRC Clinical Trials Centre, The University of Sydney, Sydney, New South Wales, Australia

Karen Schuck

Department of Rheumatology, Royal North Shore Hospital, Northern Clinical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia

Kirsty Carmichael

Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia

R O'Connell

NHMRC Clinical Trials Centre, The University of Sydney, Sydney, New South Wales, Australia

Thomas Buttel

Representative of People with Knee Osteoarthritis, Sydney, New South Wales, Australia