The translational significance of epithelial‐mesenchymal transition in head and neck cancer

Christian A Graves; Fadi F Abboodi; Swati Tomar; James Wells; Lucia Pirisi

doi:10.1186/s40169-014-0039-9

Clinical and Translational Medicine (Dec 2014)

The translational significance of epithelial‐mesenchymal transition in head and neck cancer

Christian A Graves,
Fadi F Abboodi,
Swati Tomar,
James Wells,
Lucia Pirisi

Affiliations

Christian A Graves: Department of PathologyMicrobiology & ImmunologyUniversity of South Carolina School of MedicineBldg. 1 Room B43 6439 Garners Ferry Rd29208ColumbiaSCUSA
Fadi F Abboodi: Department of PathologyMicrobiology & ImmunologyUniversity of South Carolina School of MedicineBldg. 1 Room B43 6439 Garners Ferry Rd29208ColumbiaSCUSA
Swati Tomar: Department of PathologyMicrobiology & ImmunologyUniversity of South Carolina School of MedicineBldg. 1 Room B43 6439 Garners Ferry Rd29208ColumbiaSCUSA
James Wells: Department of Head and Neck SurgeryWm. Jennings Dorn VA Medical Center29208ColumbiaSCUSA
Lucia Pirisi: Department of PathologyMicrobiology & ImmunologyUniversity of South Carolina School of MedicineBldg. 1 Room B43 6439 Garners Ferry Rd29208ColumbiaSCUSA

DOI: https://doi.org/10.1186/s40169-014-0039-9
Journal volume & issue: Vol. 3, no. 1
pp. n/a – n/a

Abstract

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Abstract Positive markers of epithelial‐mesenchymal transition (EMT) in head and neck cancers complicate clinical management and are associated with reduced survival. We discuss recent translational discoveries in EMT and suggest additional actionable molecular pathways, biomarkers, and clinical agents.

Published in Clinical and Translational Medicine

ISSN: 2001-1326 (Online)
Publisher: Wiley
Country of publisher: Australia
LCC subjects: Medicine: Medicine (General)
Website: https://onlinelibrary.wiley.com/journal/20011326

About the journal

Abstract

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