Nature Communications (Jun 2017)

Fetal and postnatal metal dysregulation in autism

  • Manish Arora,
  • Abraham Reichenberg,
  • Charlotte Willfors,
  • Christine Austin,
  • Chris Gennings,
  • Steve Berggren,
  • Paul Lichtenstein,
  • Henrik Anckarsäter,
  • Kristiina Tammimies,
  • Sven Bölte

DOI
https://doi.org/10.1038/ncomms15493
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 10

Abstract

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The contribution of metal exposure to the etiology of ASD is unclear. Here the authors tested whether elemental dysregulation contributes to ASD risk by analysing tooth metal biomarkers from ASD discordant twins, and found significant differences in metal uptake between ASD cases and their control twin siblings, but only during certain developmental periods.