Frontiers in Pediatrics (Apr 2024)

Prevalence of SARS-CoV-2 in newborns born to SARS-CoV-2-positive mothers at 2 weeks of life

  • Sophia Jan,
  • Sophia Jan,
  • Sophia Jan,
  • Sophia Jan,
  • Robert Katz,
  • Robert Katz,
  • Robert Katz,
  • David Fagan,
  • David Fagan,
  • David Fagan,
  • Telmo Santos,
  • Telmo Santos,
  • Telmo Santos,
  • Joanna C. Beachy,
  • Caren Steinway,
  • Caren Steinway,
  • Caren Steinway,
  • Jack Chen,
  • Jack Chen,
  • Alina Tsouristakis,
  • Alina Tsouristakis,
  • Briana Mancenido,
  • Briana Mancenido,
  • Christy Leung,
  • Christy Leung,
  • Emily Moore,
  • Emily Moore,
  • Estelle Wilson,
  • Estelle Wilson,
  • Lorna Lin,
  • Lorna Lin,
  • Michael Harte,
  • Michael Harte,
  • Michelle Katzow,
  • Michelle Katzow,
  • Michelle Katzow,
  • Michelle Katzow,
  • Lorry G. Rubin,
  • Lorry G. Rubin,
  • Lorry G. Rubin,
  • Lorry G. Rubin

DOI
https://doi.org/10.3389/fped.2024.1381104
Journal volume & issue
Vol. 12

Abstract

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IntroductionLimited evidence exists on management recommendations for neonates born to SARS-CoV-2-positive mothers. This study looked at transmission risk of neonates presenting for primary care in a large regional health system within New York during the early months of the COVID-19 pandemic.MethodsThis was a prospective, observational study of newborns born to SARS-CoV-2-positive mothers presenting at any of the 19 Northwell Health-Cohen Children's Medical Center primary care practices who underwent another oropharyngeal/nasopharyngeal swab for detection of SARS-CoV-2 by day of life (DOL) 14.ResultsAmong 293 newborns born to SARS-CoV-2-positive mothers who were negative at birth, 222 were retested at DOL 14, corresponding to times with different predominant strains. Of these, seven tested positive but had no symptoms.ConclusionThe overall low transmission rates and absence of symptomatic infection support the safety of direct breastfeeding after hospital discharge with appropriate hand and breast hygiene.

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