Nature Communications (Mar 2020)

A lipophilic cation protects crops against fungal pathogens by multiple modes of action

  • Gero Steinberg,
  • Martin Schuster,
  • Sarah J. Gurr,
  • Tina A. Schrader,
  • Michael Schrader,
  • Mark Wood,
  • Andy Early,
  • Sreedhar Kilaru

DOI
https://doi.org/10.1038/s41467-020-14949-y
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 19

Abstract

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New fungicides are needed due to emerging resistance shown by crop pathogens. Here, the authors show that a mono-alkyl lipophilic cation protects plants from fungal pathogens by inhibiting fungal mitochondrial respiration, inducing production of reactive oxygen species, triggering fungal apoptosis, and activating innate plant defense.