Проблемы особо опасных инфекций (Sep 2014)

Application of Dot-Immunoassay for Detection of Plague Agent Antigens in the Field Samples

  • O. A. Noskova,
  • T. Yu. Zagoskina,
  • E. N. Subycheva,
  • E. Yu. Markov,
  • Yu. O. Popova,
  • L. G. Gridneva,
  • E. P. Mikhailov

DOI
https://doi.org/10.21055/0370-1069-2014-3-69-71
Journal volume & issue
Vol. 0, no. 3
pp. 69 – 71

Abstract

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CFU/ml) and soluble antigens (FI) − ≥ 4.8 ng/ml and high specificity, confirmed by the absence of false-positive reactions with five heterologous microorganisms. The test-systems were used for Y. pestis antigen detection in field material from the territory of the Altai mountain natural plague focus by dot-immunoassay with comparison of the received results in passive hemagglutination reaction. Test-systems possessed a number of advantages as compared to routine serological reactions and could be applied with success by practical public health services both in stationary and field conditions.

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