High-throughput immune repertoire analysis with IGoR

Quentin Marcou; Thierry Mora; Aleksandra M. Walczak

doi:10.1038/s41467-018-02832-w

Nature Communications (Feb 2018)

High-throughput immune repertoire analysis with IGoR

Quentin Marcou,
Thierry Mora,
Aleksandra M. Walczak

Affiliations

Quentin Marcou: Laboratoire de Physique Théorique, CNRS, Sorbonne Université and École Normale Supérieure (PSL)
Thierry Mora: Laboratoire de Physique Statistique, CNRS, Sorbonne Université, Université Paris-Diderot, and École normale supérieure (PSL)
Aleksandra M. Walczak: Laboratoire de Physique Théorique, CNRS, Sorbonne Université and École Normale Supérieure (PSL)

DOI: https://doi.org/10.1038/s41467-018-02832-w
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 10

Abstract

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B and T cell receptor diversity can be studied by high-throughput immune receptor sequencing. Here, the authors develop a software tool, IGoR, that calculates the likelihoods of potential V(D)J recombination and somatic hypermutation scenarios from raw immune sequence reads.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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