Emerging Infectious Diseases (Feb 2014)

Replicative Capacity of MERS Coronavirus in Livestock Cell Lines

  • Isabella Eckerle,
  • Victor M. Corman,
  • Marcel A. Müller,
  • Matthias Lenk,
  • Rainer G. Ulrich,
  • Christian Drosten

DOI
https://doi.org/10.3201/eid2002.131182
Journal volume & issue
Vol. 20, no. 2
pp. 276 – 279

Abstract

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Replicative capacity of Middle East respiratory syndrome coronavirus (MERS-CoV) was assessed in cell lines derived from livestock and peridomestic small mammals on the Arabian Peninsula. Only cell lines originating from goats and camels showed efficient replication of MERS-CoV. These results provide direction in the search for the intermediate host of MERS-CoV.

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