Revisiting Chameleon Sequences in the Protein Data Bank

Abstract

The steady growth of the Protein Data Bank (PDB) suggests the periodic repetition of searches for sequences that form different secondary structures in different protein structures; these are called chameleon sequences. This paper presents a fast (nlog(n)) algorithm for such searches and presents the results on all protein structures in the PDB. The longest such sequence found consists of 20 residues.

Keywords

• chameleon sequence
• residue propensity
• Protein Data Bank