Cytomegalovirus Infection in a Patient With Leukocyte Adhesion Deficiency Type 1

Abstract

Leukocyte adhesion deficiency type 1 (LAD-1) is a rare autosomal recessive immunodeficiency disorder, characterized by recurrent bacterial and fungal infections without pus formation. Herein, we report a case of LAD-1 that developed into gastrointestinal cytomegalovirus (CMV) disease and manifested with persistent abdominal pain and bloody diarrhea. Although the presence of concurrent gastrointestinal CMV infection with LAD-1 is a rare condition, this case highlights the need for further research to evaluate the complex mechanisms between LAD-1 and CMV occurrence.

Keywords

• Cytomegalovirus
• Leukocyte adhesion deficiency type 1
• Gastrointestinal tract
• Children