Treatment of MRSA-infected osteomyelitis using bacterial capturing, magnetically targeted composites with microwave-assisted bacterial killing

Yuqian Qiao; Xiangmei Liu; Bo Li; Yong Han; Yufeng Zheng; Kelvin Wai Kwok Yeung; Changyi Li; Zhenduo Cui; Yanqin Liang; Zhaoyang Li; Shengli Zhu; Xianbao Wang; Shuilin Wu

doi:10.1038/s41467-020-18268-0

Nature Communications (Sep 2020)

Treatment of MRSA-infected osteomyelitis using bacterial capturing, magnetically targeted composites with microwave-assisted bacterial killing

Yuqian Qiao,
Xiangmei Liu,
Bo Li,
Yong Han,
Yufeng Zheng,
Kelvin Wai Kwok Yeung,
Changyi Li,
Zhenduo Cui,
Yanqin Liang,
Zhaoyang Li,
Shengli Zhu,
Xianbao Wang,
Shuilin Wu

Affiliations

Yuqian Qiao: School of Materials Science & Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University
Xiangmei Liu: Hubei Key Laboratory of Polymer Materials, Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, School of Materials Science & Engineering, Hubei University
Bo Li: State Key Laboratory for Mechanical Behavior of Materials, School of Materials Science and Engineering, Xi’an Jiaotong University
Yong Han: State Key Laboratory for Mechanical Behavior of Materials, School of Materials Science and Engineering, Xi’an Jiaotong University
Yufeng Zheng: College of Engineering, State Key Laboratory for Turbulence and Complex System, Department of Materials Science and Engineering, Peking University
Kelvin Wai Kwok Yeung: Department of Orthopaedics & Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong
Changyi Li: Stomatological Hospital, Tianjin Medical University
Zhenduo Cui: School of Materials Science & Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University
Yanqin Liang: School of Materials Science & Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University
Zhaoyang Li: School of Materials Science & Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University
Shengli Zhu: School of Materials Science & Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University
Xianbao Wang: Hubei Key Laboratory of Polymer Materials, Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, School of Materials Science & Engineering, Hubei University
Shuilin Wu: School of Materials Science & Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University

DOI: https://doi.org/10.1038/s41467-020-18268-0
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 13

Abstract

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Deep tissue infections can be difficult to treat due to limited light penetration associated with phototherapies. Here, the authors report on a bacterial capture system for antibiotic delivery and microwave-assisted killing of MRSA in osteomyelitis and demonstrate application in vivo.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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