Prevalence of BRAF, NRAS and c-KIT mutations in Slovenian patients with advanced melanoma

Moltara Maja Ebert; Novakovic Srdjan; Boc Marko; Bucic Marina; Rebersek Martina; Zadnik Vesna; Ocvirk Janja

doi:10.2478/raon-2018-0017

Radiology and Oncology (Apr 2018)

Prevalence of BRAF, NRAS and c-KIT mutations in Slovenian patients with advanced melanoma

Moltara Maja Ebert,
Novakovic Srdjan,
Boc Marko,
Bucic Marina,
Rebersek Martina,
Zadnik Vesna,
Ocvirk Janja

Affiliations

Moltara Maja Ebert: Department of Medical Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia
Novakovic Srdjan: Department of Molecular Diagnostics, Institute of Oncology Ljubljana, Ljubljana, Slovenia
Boc Marko: Department of Medical Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia
Bucic Marina: Department of Molecular Diagnostics, Institute of Oncology Ljubljana, Ljubljana, Slovenia
Rebersek Martina: Department of Medical Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia
Zadnik Vesna: Epidemiology and Cancer Registry, Institute of Oncology Ljubljana, Ljubljana, Slovenia
Ocvirk Janja: Department of Medical Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia

DOI: https://doi.org/10.2478/raon-2018-0017
Journal volume & issue: Vol. 52, no. 3
pp. 289 – 295

Abstract

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BRAF, NRAS and c-KIT mutations are characteristics of tumour tissues that influence on treatment decisions in metastatic melanoma patients. Mutation frequency and their correlation with histological characteristics in Slovenian population have not been investigated yet.

Published in Radiology and Oncology

ISSN: 1581-3207 (Online)
Publisher: Sciendo
Country of publisher: Slovenia
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://sciendo.com/journal/RAON

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Abstract

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