The effects of Nigella sativa L. seed oil on BMI, WC and FBS in overweight men: A randomized controlled clinical trial

Abstract

Background and aims: In recent years, the wide usage of herbal drugs has encouraged the medical scientists to evaluate its effects on health. Nigella sativa L. seed (N. sativa) as an herbal drug has prescribed in some diseases such as hyperlipidemia and metabolic syndrome. This study was conducted to investigate the effects of N. sativa on weight, BMI (Body Mass Index) and FBS (Fasting Blood Sugar) in overweight men.Methods: In this randomized controlled trial, we enrolled seventy eight subjects in two groups to receive 2.5 mL N. sativa oil (n=37) or 2.5 mL paraffin oil as placebo (n=30) two times a day orally for 2 months. FBS, weight, height, and WC (Waist Circumference) of subjects were measured before and after intervention in both groups.Results: After intervention, in N. sativa group, weight, BMI, FBS, and WC were significantly reduced (P<0.01) compared with baseline and also compared with placebo group.Conclusion: Our results showed that daily intake of 5ml N. sativa oil for two months could significantly reduce weight, WC and FBS in over weight men.

Keywords

• nigella sativa
• overweight
• fasting blood sugar
• body mass index
• waist circumference