Haematologica (Mar 2008)

ETV6/GOT1 fusion in a case of t(10;12)(q24;p13)-positive myelodysplastic syndrome

  • Stephanie Struski,
  • Laurent Mauvieux,
  • Carine Gervais,
  • Catherine Hélias,
  • Kun Lun Liu,
  • Michel Lessard

DOI
https://doi.org/10.3324/haematol.11988
Journal volume & issue
Vol. 93, no. 3

Abstract

Read online

The ETV6/GOT1 fusion, resulting from t(10;12) (q24;p13), has been recently described in a myelodysplastic syndrome. We reported a second case of t(10;12)-positive myelodysplastic syndrome in whom fluorescent in situ hybridization confirmed the non-random translocation but molecular biology analyses revealed a ETV6/GOT1 chimera varying from the first case described.