EFEITO DA SUPLEMENTAÇÃO DE CAFEÍNA EM PARÂMETROS HEMATOLÓGICOS, IMUNOLÓGICOS E NO DESEMPENHO FÍSICO

Abstract

Therefore was objected to identify the effects of acute supplementation of caffeine with 8 and 16 mg.kg-1 in hematological and immunological parameters and the performance of the Wistar rats submitted in intense exercise until exhaustion. Materials and Methods: was selected 24 Wistar male rats, adults and sedentary with average weight of 174.86 + 8.26g and were randomly divided in control group (water) CON (n=8), CAF8 (n=8) (8mg/kg) e CAF16 (n=8) (16mg/kg) administered the caffeine by gavage 30 minutes before the begin of experiment. The swimming happened in an aquarium with 60 cm of depth, water at 28°C, until the exhaustion with overload of 7.5% from their weight and immediately euthanized for the withdrawal of 1ml of their blood for lab analyzes. Results: 8 mg.kg-1 e 16 mg.kg-1 do not change the performance and the last do not change both parameters. The supplementation whit 8 mg.kg-1 of caffeine was able only increase the platelets count (p<0.05) and tended decrease the immunosuppressive tendency. Conclusions 8 mg.kg-1 of caffeine was able of increase the platelets account and decrease the immunosuppressive tendency of exhaustive exercise, but, do not shows be able in increase performance and 16mg/kg of caffeine do not change all investigated parameters.

Keywords

• Caffeine Supplementation
• Hematology
• Immunology
• Performance