Frontiers in Bioscience-Landmark (Dec 2021)

Spine surgery and fat embolism syndrome. Defining the boundaries of medical accountability by hospital autopsy

  • Davide Radaelli,
  • Martina Zanon,
  • Monica Concato,
  • Paolo Fattorini,
  • Letizia Alfieri,
  • Raffaella Marino,
  • Margherita Neri,
  • Luigi Cipolloni,
  • Stefano D’Errico

DOI
https://doi.org/10.52586/5067
Journal volume & issue
Vol. 26, no. 12
pp. 1760 – 1768

Abstract

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Background: Fat Embolism Syndrome (FES) is a clinical condition characterized by neurological, respiratory, hematological and cutaneous manifestations. Fatal FES has been described as a rare complication during or after spinal elective surgery. The investigation of the cause of death in fatalities related with spine surgery should be mandatory to exclude or confirm fat embolism; a detailed methodological approach to the body in these cases suggests to provide a cautious dissection of surgical site and collection of samples to detect embolized fat globules in vessels. Methods: Two fatal cases of fat embolism syndrome after posterior spinal fusion are presented. Conclusions: A complete post mortem examination by means of histochemical and immunohistochemical analysis explained the cause of death and prevented medical malpractice litigation.

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