Mediators of Inflammation (Jan 2002)

Evidence for local inflammation in complex regional pain syndrome type 1

  • Frank J. P. M. Huygen,
  • Anke G. J. de Bruijn,
  • Martha T. de Bruin,
  • J. George Groeneweg,
  • Jan Klein,
  • Freek J. Zijlstra

DOI
https://doi.org/10.1080/09629350210307
Journal volume & issue
Vol. 11, no. 1
pp. 47 – 51

Abstract

Read online

Background: The pathophysiology of complex regional pain syndrome type 1 (CRPS 1) is still a matter of debate. Peripheral afferent, efferent and central mechanisms are supposed. Based on clinical signs and symptoms (e.g. oedema, local temperature changes and chronic pain) local inflammation is suspected.