Phosphatase Activity in Chemical Cholera Vaccine and its Components

Abstract

Presented are the data on detection and characterization of phosphomonoesterase and phosphodiesterase activities in detoxicated cultural fluid of production Vibrio cholerae strains 569B and M41, and in choleragen-anatoxin and O-antigenic fraction, the vaccine components. These enzymes were demonstrated to be present in the cholera vaccine tablet, thus its biochemical properties were characterized more completely.

Keywords

• холерная вакцина
• компоненты вакцины
• фосфомоноэстераза
• фосфодиэстераза
• cholera vaccine
• vaccine components
• phosphomonoesterase
• phosphodiesterase