Communications Biology (Sep 2022)

Structural and mutational analysis of MazE6-operator DNA complex provide insights into autoregulation of toxin-antitoxin systems

  • Khushboo Kumari,
  • Siddhartha P. Sarma

DOI
https://doi.org/10.1038/s42003-022-03933-5
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 14

Abstract

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The dimeric MazE6 antitoxin binds to a specific sequence in its cognate operator DNA for autoregulation, and the key residues for dimerization and DNA binding are identified.