Oxalamide Based Fe(II)-MOFs as Potential Electrode Modifiers for Glucose Detection

Panagiotis Oikonomopoulos; Varvara Pagkali; Evangelia Kritikou; Anthi Panara; Marios G. Kostakis; Nicolaos S. Thomaidis; Thomais G. Tziotzi; Anastasios Economou; Christos Kokkinos; Giannis S. Papaefstathiou

doi:10.3390/chemistry5010002

Chemistry (Dec 2022)

Oxalamide Based Fe(II)-MOFs as Potential Electrode Modifiers for Glucose Detection

Panagiotis Oikonomopoulos,
Varvara Pagkali,
Evangelia Kritikou,
Anthi Panara,
Marios G. Kostakis,
Nicolaos S. Thomaidis,
Thomais G. Tziotzi,
Anastasios Economou,
Christos Kokkinos,
Giannis S. Papaefstathiou

Affiliations

Panagiotis Oikonomopoulos: Laboratory of Inorganic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece
Varvara Pagkali: Laboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece
Evangelia Kritikou: Laboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece
Anthi Panara: Laboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece
Marios G. Kostakis: Laboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece
Nicolaos S. Thomaidis: Laboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece
Thomais G. Tziotzi: Department of Chemistry, University of Crete, Voutes, 71003 Herakleion, Greece
Anastasios Economou: Laboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece
Christos Kokkinos: Laboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece
Giannis S. Papaefstathiou: Laboratory of Inorganic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece

DOI: https://doi.org/10.3390/chemistry5010002
Journal volume & issue: Vol. 5, no. 1
pp. 19 – 30

Abstract

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In an attempt to expand the coordination chemistry of N,N′-bis(2,4-dicarboxyphenyl)-oxalamide (H6L) ligand, we isolated and structurally characterized two new Fe(II) Metal-Organic Frameworks (MOFs), namely [Fe2(H2L)(H2O)5] (3D-Fe-MOF) and [Fe(H4L)(H2O)2]∙2H2O, (2D-Fe-MOF) by carefully adjusting the reaction conditions to achieve the optimal degree of deprotonation of the bridging ligand. Both MOFs were found stable in water, as evidenced by powder X-ray diffraction data and their ability to sorb glucose (GLU) from either an aqueous solution or artificial sweat was investigated only to show negligible sorption. A graphite paste sensor (GPE) using the 3D-Fe-MOF as a modifier was fabricated. The 3D-Fe-MOF modified GPE was assessed for non-enzymatic GLU detection in aqueous solution at pH 6 via differential pulse voltammetry and the preliminary results were discussed.

Published in Chemistry

ISSN: 2624-8549 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry
Website: https://www.mdpi.com/journal/chemistry

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