BMC Research Notes (Aug 2021)

Microarray analysis of ductal carcinoma in situ samples obtained by puncture from surgical resection specimens

  • Tomoo Jikuzono,
  • Eriko Manabe,
  • Shoko Kure,
  • Haruki Akasu,
  • Tomoko Ishikawa,
  • Yoko Fujiwara,
  • Masujiro Makita,
  • Osamu Ishibashi

DOI
https://doi.org/10.1186/s13104-021-05760-z
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 4

Abstract

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Abstract Objective The incidence of ductal carcinoma in situ (DCIS) is increasing due to more widespread mammographic screening. DCIS, the earliest form of breast cancer, is non-invasive at the time of detection. If DCIS tissues are left undetected or untreated, it can spread to the surrounding breast tissue. Thus, surgical resection is the standard treatment. Understanding the mechanism underlying the non-invasive property of DCIS could lead to more appropriate medical treatments, including nonsurgical options. Data description We conducted a microarray-based genome-wide transcriptome analysis using DCIS specimens obtained by puncture from surgical specimens immediately after surgery.

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