Nature Communications (May 2022)
Insights into methionine S-methylation in diverse organisms
- Ming Peng,
- Chun-Yang Li,
- Xiu-Lan Chen,
- Beth T. Williams,
- Kang Li,
- Ya-Nan Gao,
- Peng Wang,
- Ning Wang,
- Chao Gao,
- Shan Zhang,
- Marie C. Schoelmerich,
- Jillian F. Banfield,
- J. Benjamin Miller,
- Nick E. Le Brun,
- Jonathan D. Todd,
- Yu-Zhong Zhang
Affiliations
- Ming Peng
- Frontiers Science Center for Deep Ocean Multispheres and Earth System & College of Marine Life Sciences, Ocean University of China
- Chun-Yang Li
- Frontiers Science Center for Deep Ocean Multispheres and Earth System & College of Marine Life Sciences, Ocean University of China
- Xiu-Lan Chen
- State Key Laboratory of Microbial Technology, Marine Biotechnology Research Center, Shandong University
- Beth T. Williams
- School of Biological Sciences, University of East Anglia
- Kang Li
- Laboratory for Marine Biology and Biotechnology, Pilot National Laboratory for Marine Science and Technology
- Ya-Nan Gao
- Frontiers Science Center for Deep Ocean Multispheres and Earth System & College of Marine Life Sciences, Ocean University of China
- Peng Wang
- Frontiers Science Center for Deep Ocean Multispheres and Earth System & College of Marine Life Sciences, Ocean University of China
- Ning Wang
- State Key Laboratory of Microbial Technology, Marine Biotechnology Research Center, Shandong University
- Chao Gao
- State Key Laboratory of Microbial Technology, Marine Biotechnology Research Center, Shandong University
- Shan Zhang
- State Key Laboratory of Microbial Technology, Marine Biotechnology Research Center, Shandong University
- Marie C. Schoelmerich
- Department of Earth and Planetary Science, Innovative Genomics Institute Building, University of California, Berkeley
- Jillian F. Banfield
- Department of Earth and Planetary Science, Innovative Genomics Institute Building, University of California, Berkeley
- J. Benjamin Miller
- School of Biological Sciences, University of East Anglia
- Nick E. Le Brun
- Centre for Molecular and Structural Biochemistry, School of Chemistry, University of East Anglia
- Jonathan D. Todd
- School of Biological Sciences, University of East Anglia
- Yu-Zhong Zhang
- Frontiers Science Center for Deep Ocean Multispheres and Earth System & College of Marine Life Sciences, Ocean University of China
- DOI
- https://doi.org/10.1038/s41467-022-30491-5
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 15
Abstract
S-methyl methionine (SMM) is a key molecule in production of dimethylsulfoniopropionate (DMSP), an important marine anti-stress compound, with roles in global nutrient cycling. Here, the authors determine the mechanism of SMM synthesis and uncover unexpected roles for SMM in archaea, CPR bacteria and animals.
