Anales de la Facultad de Medicina (Dec 2014)
Identification of alcohol and cocaine derivatives in pregnacy in meconium samples.
Abstract
The consumption of alcohol and cocaine can affect pregnant’s health, fetus´s health and child development, so it is important to recognize fetal exposure to these substances in order to plan appropriate monitoring and timely interventions. The aim of the study was to determine the frequency of alcohol consumption and cocaine intake in the Hospital Pereira Rossell’s (Montevideo, Uruguay) population. The investigation consisted on an observational analytic cross-sectional study of 240 puerperal women and their children born at the Hospital Pereira Rossell from November 2010 to March 2011. The method used for the identification of free fatty acid ethyl esters in meconium of newborns was developed at the Polo Tecnológico de Pando, Facultad de Química, Universidad de la República for this investigation. The media of maternal age was 25; Alcohol consumption during pregnancy was admitted by 81 women, and the presence of free fatty acids ethyl esters was confirmed in 113 cases (49.78%); the consumption of cocaine hydrochloride and freebase cocaine was positive in 9.25% cases. Alcohol consumption was identified in half of pregnant women. The consumption of cocaine derivatives in the population studied was high. Exposed fetus can be identified with the analysis of meconium samples, with more certainty than by reports of patients.
