The prognostic value of tumor budding in gastric adenocarcinomas: A cross-sectional study

Abstract

Background : : Tumor budding is a negative prognostic factor for many solid malignancies. We investigated the relationship between patients' clinicopathological characteristics and tumor budding, as well as the effect of budding level on prognosis. Methods : : In this retrospective, cross-sectional, and descriptive study at a tertiary university hospital, 104 patients with gastric adenocarcinoma were divided into two groups according to whether they had a high (Results : : Sixty-two patients had a low level of budding and 42 had a high level of budding. The mean time from the first diagnosis to the last followup was significantly longer (P Conclusion : : Our study supports that budding is a negative prognostic factor in gastric cancer.

Keywords

• adenocarcinoma; prognosis; stomach neoplasms